Plasmon-based targeted Hypertermia

Project description

Exploiting the unique capability of plasmonic nanoparticles to generate heat on the nanometer scale, we study the use of functionalized gold nanoparticles as efficient photothermal agents for specific ablation of cancer tissues upon laser illumination. The technology is currently tested on animal models with special emphasis on developing the optimum physical and biochemical conditions to maximize the efficacy of the treatment.

ICFO groups associated with the project

Prof. Dr. Turgut Durduran
Medical Optics

ICFO publications associated with the project

Imaging of Plasmonic Heating in a Living Organism
J.S. Donner, S.A. Thompson, C. Alonso-Ortega, J. Morales, L.G. Rico, S.I.C.O. Santos, and R. Quidant,
ACS Nano, vol. 7, pp. 8666-8672, 2013.
Photoinduced Heating of Nanoparticle Arrays
G. Baffou, P. Berto, E. Bermúdez Ureña, R. Quidant, S. Monneret, J. Polleux, and H. Rigneault,
ACS Nano, vol. 7, pp. 6478-6488, 2013.
Mapping Intracellular Temperature Using Green Fluorescent Protein
J.S. Donner, S.A. Thompson, M.P. Kreuzer, G. Baffou, and R. Quidant,
Nano Letters, vol. 12, pp. 2107-2111, 2012.
Thermo‐plasmonics: using metallic nanostructures as nano‐sources of heat
G. Baffou, and R. Quidant,
Laser & Photonics Reviews, vol. 7, pp. 171-187, 2012.

External collaborations

IDIBELL

Funding

Fundacio Privada CELLEX Barcelona