BioNano activities

Detection of multiple Sepsis biomarkers

Ultra-sensitive bio-sensing and bio-nanodevices

Project description

We are developing a small footprint and large field of view microscope whose detection is based on the interference of partially overlapped light beams revealed by a CMOS image sensor. The new design is based on the use of birefringent plates (Savart plate) which allows to shear beams maintaining them unfocused and parallel. We have already demonstrated the capability to detect sub-nanometric transparent features in glass and single layer of proteins. We also coordinate the European H2020 project RAIS that aims to develop this technology for point of care fast detection of Sepsis, the most spread infectious disease that causes millions of deaths worldwide.

ICFO groups associated with the project

External collaborations

École Polytechnique Fédérale De Lausanne (EPFL) – Switzerland. Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC) – Spain. microTEC Gesellschaft für Mikrotechnologie mbH (microTEC) – Germany. Trinean NV – Belgium . Institut Català De La Salut – Hospital Universitari Vall D’Hebron (ICS-HUVH) – Spain. B R A H M S GmbH (part of Thermo Fisher Scientific) – Germany. iXscient Ltd – UK. DIESSE Diagnostica Senese S.p.A. – Italy

Selected publications in this project

No publications linked to this project


  • ICFO to coordinate RAIS- H2020 project

    Photonics KET – Biophotonics for screening of diseases. Officially launched on 1 January, 2015 with the formal kick-off meeting taking place at ICFO on 19 January, the Horizon 2020 project RAIS (Scalable, point-of-care and label free microarray platform for rapid detection of Sepsis) is now in motion. The project will be coordinated by ICREA Professor … Continue reading →


European Union’s Horizon 2020 research and innovation programme under grant agreement no. 644956
Fundacio Privada CELLEX Barcelona
Spanish Ministry of Economy and Competitiveness (MINECO), through European Regional Development Fund (FEDER) through grant TEC2013-46168-R

▲ Detection of multiple Sepsis biomarkers